Diabetes can affect sight
If you have diabetes mellitus, your body does not use and
store sugar properly. High blood-sugar levels can damage blood vessels in
the retina, the nerve layer at the back of the eye that senses light and
helps to send messages to the brain. The damage to retinal vessels is referred
to as diabetic retinopathy.
Types of diabetic retinopathy
There are two types of diabetic retinopathy: nonproliferative
diabetic retinopathy (NPDR) and proliferative diabetic retinopathy
(PDR). NPDR, commonly known as background retinopathy, is an early
stage of diabetic retinopathy.
In this stage, tiny blood vessels within the retina leak
blood or fluid. The leaking fluid causes the retina to swell or to form
deposits called exudates. Many people with diabetes have mild NPDR, which
usually does not affect their vision. When vision is affected it is the
result of macular edema and/or macular ischemia.
- Macular edema is swelling, or thickening, of
the macula, a small area in the center of the retina that allows us
to see fine details clearly. The swelling is caused by fluid leaking
from retinal blood vessels. It is the most common cause of visual loss
in diabetes. Vision loss may be mild to severe, but even in the worst
cases, peripheral vision continues to function.
- Macular ischemia occurs when small blood vessels
(capillaries) close. Vision blurs because the macula no longer receives
sufficient blood supply to work properly.
PDR
is present when abnormal new vessels (neovascularization) begin growing
on the surface of the retina or optic nerve. The main cause of PDR is widespread
closure of retinal blood vessels, preventing adequate blood flow. The retina
responds by growing new blood vessels in an attempt to supply blood to the
area where the original vessels closed.
Unfortunately, the new, abnormal blood vessels do not
resupply the retina with normal blood flow. The new vessels are often
accompanied by scar tissue that may cause wrinkling or detachment of the
retina.
PDR may cause more severe vision loss than NPDR because
it can affect both central and peripheral vision. Proliferative diabetic
retinopathy causes visual loss in the following ways:
Vitreous hemorrhage:
The fragile new vessels may bleed into the vitreous, a clear,
jelly-like substance that fills the center of the eye. If the vitreous hemorrhage
is small, a person might see only a few new dark floaters. A very large
hemorrhage might block out all vision.
It may take days, months or even years to reabsorb the
blood, depending on the amount of blood present. If the eye does not clear
the vitreous blood adequately within a reasonable time, vitrectomy surgery
may be recommended
Vitreous hemorrhage alone does not cause permanent vision
loss. When the blood clears, visual acuity may return to its former level
unless the macula is damaged.
Traction retinal detachment:
When PDR is present, scar tissue associated with neovascularization
can shrink, wrinkling and pulling the retina from its normal position. Macular
wrinkling can cause visual distortion. More severe vision loss can occur
if the macula or large areas of the retina are detached.
Neovascular glaucoma:
Occasionally, extensive retinal vessel closure will cause
new, abnormal blood vessels to grow on the iris (colored part of the eye)
and block the normal flow of fluid out of the eye. Pressure in the eye builds
up, resulting in neovascular glaucoma, a severe eye disease that causes
damage to the optic nerve.
How is diabetic retinopathy diagnosed?
A medical eye examination is the only way to find changes
inside your eye. An Ophthalmologist can often diagnose and treat serious
retinopathy before you are aware of any vision problems. The Ophthalmologist
dilates your pupil and looks inside of the eye with an ophthalmoscope.
If your Ophthalmologist finds diabetic retinopathy,
he or she may order color photographs of the retina or a special test
called fluorescein angiography to find out if you need treatment. In this
test eye a dye is injected in your arm and photos of your eye are taken
to detect where fluid is leaking.
How is diabetic retinopathy treated?
The best treatment is to prevent the development of retinopathy
as much as possible. Strict control of your sugar will significantly reduce
the long-term risk of vision loss from diabetic retinopathy. If high blood
pressure and kidney problems are present, they need to be treated. Smoking
can aggravate the complications of diabetes.
Laser surgery:
Laser
surgery is often recommended for people with macular edema, PDR and neovascular
glaucoma. For macular edema, the laser is focused on the damaged retina
near the macula to decrease the fluid leakage. The main goal of treatment
is to prevent further loss of vision. It is uncommon for people who have
blurred vision from macular edema to recover normal vision, although some
may experience partial improvement. A few people may see the laser spots
near the center of their vision following treatment. The spots usually fade
with time, but may not disappear. For PDR, the laser
is focused on all parts of the retina except the macula. This panretinal
photocoagulation treatment causes abnormal new vessels to shrink and often
prevents them from growing in the future. It also decreases the chance that
vitreous bleeding or retinal distortion will occur.
Multiple laser treatments over time are sometimes necessary.
Laser surgery does not cure diabetic retinopathy and does not always prevent
further loss of vision.
Vitrectomy:
In advanced PDR, the Ophthalmologist may recommend a vitrectomy.
During this microsurgical procedure, which is performed in the operating
room, the blood-filled vitreous is removed and replaced with a clear solution.
The Ophthalmologist may wait for several months or up to a year to see if
the blood clears on its own before performing the vitrectomy.
Vitrectomy often prevents further bleeding by removing
the abnormal vessels that caused the bleeding. If the retina is detached,
it can be repaired during the vitrectomy surgery. Surgery should usually
be done early because macular distortion or traction retinal detachment
will cause permanent visual loss. The longer the macula is distorted or
out of place, the more serious the vision loss will be.
Vision loss is largely preventable
If you have diabetes, it is important to know that today,
with improved methods of diagnosis and treatment, only a small percentage
of people who develop retinopathy have serious vision problems. Early detection
of diabetic retinopathy is the best protection against loss of vision.
You can significantly lower your risk of vision loss by maintaining strict
control of your blood sugar and visiting your Ophthalmologist regularly.
When to schedule an examination
People with diabetes should schedule dilated eye examinations
at least once a year. More frequent medical eye examinations may be necessary
after diabetic retinopathy has been diagnosed.
Pregnant women with diabetes should schedule an appointment
in the first trimester because retinopathy can progress quickly during
pregnancy.
If you need to be examined for glasses, it is important
that your blood sugar be in consistent control for at least two weeks when
you see your Ophthalmologist. Glasses that work well when the blood sugar
is out of control will not work well when sugar is stable. Rapid changes
in blood sugar can cause fluctuating vision in both eyes even if retinopathy
is not present.
You should have your eyes checked promptly if you have
visual changes that:
- Affect only one eye;
- Last more than a few days;
- Are not associated with a change in blood sugar.
When you are first diagnosed with diabetes, you should have
your eyes checked:
- Within five years of the diagnosis if you are 30 years
old or younger.
- Within a few months of the diagnosis if you are older
than 30 years
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©American Academy of Ophthalmology
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